ABSTRACT

Background. Traditional medicine is widely used by people since time immemorial and there is a tendency to increase. Traditional medicine is a product made from natural material type and nature of its content is very diverse so as to ensure the required quality of traditional medicine with a good way of making more attention to the production and handling of raw materials. One is the use of traditional medicine in addressing sleep disorders, One of the plants that is widely used by Indonesian people for the purposes of vegetable is kale plants. Some people who have been consuming vegetables kale claimed to feel sleepy. Water spinach containing alkaloids have potential asa sedativeandcan overcome sleep disorders. Therefore, weneed a scientific test to prove the truth of the allegations.
Method. This research isan experimental laboratory to design a post-test only control group design. The samples used wereas many as 25 tails of mice with body weight of 20-25 grams. Then divided into 5 experimental groups, each of which groups of 5 mice. Analysis of the data using the Shapiro-Wilk test, Kruskal-Wallis, and Post hoc / Mann-Whitney.
Results. The results showed that mice given water extracts of spinach (Ipomoea Aquatica) dose of 1 mg / 20grBB, 2 mg / 20grBB, and 4 mg / 20grBB capable of providing sedation to see passivity and righting reflex showed significant differences (p =