ABSTRACT
Background: Diabetic foot ulcers is an infection, ulceration or destruction of the connective tissue associated with neuropathy and peripheral vascular disease of the lower limbs. DM easily infected ulcers due to immune responses in patients with DM usually decreases. Bacterial infection is not the direct cause of diabetic ulcers but can slow healing infections, causing deformity and death. Patterns of bacteria and sensitivity to antibiotics in diabetic ulcers vary in each region and even hospitals.
Objective: To determine the profiles of bacteria and determine antibiotic sensitivity in diabetic foot ulcers in the General Hospital Anutapura Palu period from January to December, 2014.
Methods: This study is a qualitative research with an observational study design. Techniques probability sampling done by total sampling.
Results: There were 14 types of bacteria such as: Staphylococcus aureus (24.39%), Staphylococcus saprophyticus (2.44%), E. coli (9.75%), Citrobacter freundii (17.07%), Citrobacter Diversus (4, 88%), Streptococcus faecalis (4.88%), Streptococcus mutans (4.88%), Proteus vulgaris (4.88%), Proteus mirabilis (4.88%), Alcaligenes faecalis (4.88%), Enterobacter aerogenes (7.32%), Pseudomonas paucimobilis (2.44%), Serratia marcescens (4.88%), and Kurthia Sp. (2.44%). Antibiotics that have a high sensitivity that meropenem (48.78%), cefotaxime (26.82%), and levofloxacin (26.82%) while the lowest is vancomycin (0%) and methicillin (0%).
Conclusion: This type of bacteria is Staphylococcus aureus majority, by their nature most gram-negative staining and meropenem is an antibiotic that has the highest sensitivity.
Keywords: Profile bacteria, antibiotic sensitivity, Diabetic Foot Ulcers.
P
ABSTRAK
Latar Belakang: Ulkus kaki diabetik adalah infeksi, ulserasi atau destruksi jaringan ikat dalam yang berhubungan dengan neuropati dan penyakit vaskuler perifer pada tungkai bawah. Ulkus DM mudah terinfeksi karena respons kekebalan tubuh pada penderita DM biasanya menurun. Infeksi bakteri bukanlah penyebab langsung dari ulkus diabetikum tetapi infeksi dapat memperlambat penyembuhan, menyebabkan deformitas dan kematian. Pola bakteri dan sensitivitas terhadap antibiotik pada ulkus diabetikum berbeda-beda pada tiap daerah bahkan rumah sakit.
Tujuan: Untuk mengetahui mengetahui profil bakteri dan sensitivitas antibiotik pada ulkus kaki diabetik di Rumah Sakit Umum Anutapura Palu periode JanuariDesember 2014.
Metode: Penelitian ini merupakan jenis penelitian kualitatif dengan desain penelitian observasional deskriptif. Teknik pengambilan sampel dilakukan secara probability dengan cara total sampling.
Hasil: Didapatkan 14 jenis bakteri yakni : Staphylococcus aureus (24,39%), Staphylococcus saprophyticus (2,44%), E.coli (9,75%), Citrobacter freundii (17,07%), Citrobacter diversus (4,88%), Streptococcus faecalis (4,88%), Streptococcus mutans (4,88%), Proteus vulgaris (4,88%), Proteus mirabilis (4,88%), Alcaligenes faecalis (4,88%), Enterobacter aerogenes (7,32%), Pseudomonas paucimobilis (2,44%), Serratia marcescens (4,88%), dan Kurthia
Sp. (2,44%). Antibiotik yang memiliki sensitivitas tinggi yaitu meropenem (48,78%), cefotaxime (26,82%), dan levofloxacin (26,82%) sedangkan yang terendah yaitu vancomycin (0%) dan methicillin (0%).
Kesimpulan: Jenis bakteri yang terbanyak yaitu Staphylococcus aureus, berdasarkan sifat pewarnaan terbanyak yaitu gram negatif dan meropenem merupakan antibiotik yang memiliki sensitivitas tertinggi.
Kata Kunci: Profil bakteri, Sensitivitas antibiotik, Ulkus Kaki Diabetik.