ABSTRACT
Background: One of the plants that can be used as an herbal remedy is Kleinhovia hospita Linn, which can be found in the tropical areas. In Central Sulawesi, particularly in Palu city, Kleinhovia hospita Linn is also known as Balaroa by the local citizens. Staphylococcus aureus is a normal human flora that often cause disease and became one of the bacteria that are already experiencing a state of resistance to antibiotics. As an alternative to the use of antibiotics has led to a lot of resistance, one of the alternative ways that can be done is to use an antibacterial derived from nature. Methods: This study is a posttest control group only experimental design by using agar diffusion method for anti bacterial activity test and measure the inhibition area. The concentration extract of Balaroa leaf that tested were 10%, 25%, 50%, 100%, with Ciprofloxacin as a positive control and distilled water as a negative control. Each the concentration was replicated four times. Results: The results showed that the extract of Balaroa leaf may inhibit the growth of Staphylococcus aureus in all concentration tested. Results obtained value of the minimum inhibitory concentration was 10%. Results of statistical test by using one-way ANOVA significance value of p