ADELIA NUR FITRIANA N 101 13 031 Primary Author mixed material bibliography Palu PSPD 2017 id Indonesia

Skripsi Kedokteran

x , 54 hlm ; 29 cm CORRELATION BETWEEN LEUKOCYTE, HEMOGLOBIN, HEMATOCRIT AND THROMBOCYT LEVELS WITH THE CLINICAL DEGREE OF DENGUE HEMORRHAGIC FEVER DISEASE IN ADULT PATIENTS AT RSUD UNDATA PALU Adelia Nur Fitriana*, Muh. Ardi Munir**, Gabriella Lintin** *Medical student, Faculty of Medicine, Tadulako University ** Department of Anatomy, Faculty of Medicine, Tadulako University ABSTRACT Background: Dengue fever is a world health problem especially throughout the tropics and sub-tropics in the world. The diagnosis of DHF is still based on the WHO standard in 1997 which consists of four clinical criteria and two laboratory criteria. Routine blood examinations such as leukocyte, hemoglobin, hematocrit and platelets are expected to assist in classifying and managing patients on the basis of their clinical degrees. Objective: To understand the correlation between leucocyte, hemoglobin, hematocrit and platelets levels with clinical degree of dengue hemorrhagic fever disease in adults patients at RSUD Undata Palu. Methods: This was observational analytic research with cross-sectional method. The sampling technique was total sampling. The samples were used in this study are 84 patients according to the inclusion and exclusion criteria. The instrument in this research were medical records of adult patients with dengue hemorrhagic fever disease. The correlation between leucocyte, hemoglobin, hematocrit and platelet levels with clinical degree of dengue hemorrhagic fever disease in adult patients were analyzed using Pearson correlation test. Results: The Pearson correlation test showed there was a significant weak negative correlation between leukocytes levels with the clinical degree of dengue hemorrhagic fever in adult patients (p=0,001, r=-0,347), a significant weak positive correlation between hematocrit levels with the clinical degree of dengue hemorrhagic fever in adults patients (p=0,047, r=0,218). There was no correlation between hemoglobin levels with the clinical degree of dengue hemorrhagic fever in adult patients (p=0,290, r=0,117), and there was no correlation between platelet levels with the clinical degree of dengue hemorrhagic fever in adult patients (p=0,105, r=-0,178) Conclusions: There is a correlation between leukocyte and hematocrit levels with the clinical degree of dengue hemorrhagic fever in adult patients at RSUD Undata Palu and there was no correlation between platelets and hemoglobin levels with the clinical degree of dengue hemorrhagic fever in adult patients at RSUD Undata Palu. Keywords: Clinical degree of DHF, leukocyte levels, hemoglobin levels, hematocrit levels, platelet levels. 2 HUBUNGAN KADAR LEUKOSIT, HEMOGLOBIN, HEMATOKRIT DAN TROMBOSIT DENGAN DERAJAT KLINIS PENYAKIT DEMAM BERDARAH DENGUE PASIEN DEWASA DI RSUD UNDATA PALU Adelia Nur Fitriana*, Muh. Ardi Munir**, Gabriella Lintin** *Mahasiswa Program Studi Kedokteran, Fakultas Kedokteran, Universitas Tadulako **Departemen Anatomi, Fakultas Kedokteran, Universitas Tadulako ABSTRAK Latar Belakang: Demam berdarah merupakan masalah kesehatan masyarakat utamanya di seluruh daerah tropis dan sub-tropis di dunia. Diagnosis DBD masih berdasarkan patokan WHO Tahun 1997 yang terdiri dari empat kriteria klinis dan dua kriteria laboratorik. Pemeriksaan penunjang darah rutin seperti kadar leukosit, hemoglobin, hematokrit dan trombosit diharapkan membantu dalam mengelompokkan dan mengelola pasien berdasarkan derajat kliniknya. Tujuan: Untuk mengetahui hubungan kadar leukosit, hemoglobin, hematokrit dan trombosit dengan derajat klinis penyakit demam berdarah dengue pasien dewasa di RSUD Undata Palu Metode: Jenis penelitian yang digunakan adalah observasional analitik dengan metode cross-sectional. Teknik pengambilan sampel yang digunakan yaitu total sampling. Jumlah sampel yang digunakan dalam penelitian berjumlah 84 pasien yang sesuai dengan kriteria inklusi serta ekslusi. Instrumen yang digunakan dalam penelitian adalah data rekam medis dari pasien dewasa penderita demam berdarah dengue. Hubungan antara kadar leukosit, hemoglobin, hematokrit dan trombosit dengan derajat klinis penyakit demam berdarah dengue pada pasien dewasa dianalisis dengan menggunakan uji korelasi Pearson. Hasil: Hasil uji korelasi Pearson menunjukkan bahwa terdapat hubungan negatif lemah yang bermakna antara kadar leukosit dengan derajat klinis penyakit demam berdarah dengue pasien dewasa (p=0,001, r=-0,347), hubungan positif lemah yang bermakna antara kadar hematokrit dengan derajat klinis penyakit demam berdarah dengue pasien dewasa (p=0,047, r=0,218). Tidak terdapat hubungan antara kadar hemoglobin dengan derajat klinis penyakit demam berdarah dengue pasien dewasa (p=0,290, r=0,117), dan tidak terdapat hubungan antara kadar trombosit dengan derajat klinis penyakit demam berdarah dengue pasien dewasa (p=0,105, r=-0,178). Kesimpulan: Terdapat hubungan antara kadar leukosit dan kadar hematokrit dengan derajat klinis penyakit demam berdarah dengue pasien dewasa di RSUD Undata Palu walaupun kekuatan hubungan lemah dan tidak terdapat hubungan antara kadar hemoglobin dan kadar trombosit dengan derajat klinis penyakit demam berdarah dengue pasien dewasa di RSUD Undata Palu. Kata Kunci: Derajat Klinis DBD, Kadar Leukosit, Kadar Hemoglobin, Kadar Hematokrit, Kadar Trombosit ADELIA NUR FITRIANA N 101 13 031 DEMAM BERDARAH NONE PERPUSTAKAAN FAKULTAS KEDOKTERAN UNIVERSITAS TADULAKO N 101 13 031 FIT a SKD2017495 My Library N 101 13 031 FIT a 2369 2017-08-29 09:08:27 2017-08-29 09:08:27 machine generated